职称：研究助理教授
研究方向：密码子使用偏好与翻译调控
Email：20261371@fyust.edu.cn
李湛彪博士，于云南大学生命科学学院获得生物化学与分子生物学的博士研究生学位。博士期间，进行密码子使用与翻译调控方面的研究。在Nucleic acids research和 Science advances等杂志上发表多篇文章。
云南大学 生物化学与分子生物学 理学博士
云南大学 生物技术 理学学士
核糖体的翻译调控过程对基因表达是重要的。而转录本的密码子使用、tRNA种类及tRNA上碱基修饰会显著影响核糖体的翻译过程，甚至会导致核糖体停滞和翻译移码。基于此，探究退行性疾病中的翻译行为，并解析异常的翻译行为对细胞稳态的影响。
1. Xiuwen Li#, Zhanbiao Li#, Yingshui Zhou#, Shimin Gong, Zhenjing Chen, Jingyang Li, Miaomiao Guo, Xiaoqian Gu, Fei Li, Jiayu Wei, Tao Zhong, Tong Yin, Tianran Li, Fan Lai*, Yunkun Dang*, Guiping Ren*, RNA G-quadruplex promotes codon repeat-associated ribosomal frameshifting in human gene, Nucleic Acids Research (2026) 54(2).
2. Guiping Ren#, Xiaoqian Gu#, Lu Zhang, Shimin Gong, Shuang Song, Shunkai Chen, Zhenjing Chen, Xiaoyan Wang, Zhanbiao Li, Yingshui Zhou, Longxi Li, Jiao Yang, Fan Lai*, Yunkun Dang*, Ribosomal frameshifting at normal codon repeats recodes functional chimeric proteins in human. Nucleic Acids Research (2024), 52(5):2463-2479.
3. Qiaojia Lu, Muqun Yu, Xianyun Sun, Xin Zhou, Rui Zhang, Yahao Zhang, Xiao-Lan Liu, Zhanbiao Li, Lei Cai, Hongwei Liu, Shaojie Li, Yunkun Dang, Xiaodong Xu, Qun He, Yi Liu, Xiao Liu, Circadian clock is critical for fungal pathogenesis by regulating zinc starvation response and secondary metabolism, Science Advances (2025) 11(13).
4. Yulin Yang, Zeyu Duan, Xiao-Lan Liu, Zhanbiao Li, Zhenghao Shen, Shimin Gong, Qiaojia Lu, Yue Hu, Linhao Song, Zeyu Wang, Xuemei Cao, Yunkun Dang, Linqi Wang, Qun He, Xiao Liu. Checkpoint kinases regulate the circadian clock after DNA damage by influencing chromatin dynamics. Nucleic Acids Research (2025) 53(5).
