北京大学 神经生物学专业 博士

云南大学 生物技术专业 学士学位

利用双光子显微成像技术，主要研究睡眠在大脑发育过程中的功能以及学习与记忆相关的突触可塑性。探索在正常生理条件下或病理状态下（如孤独症，阿尔茨 海默症）小鼠大脑皮层突触可塑性以及神经元结构和功能的变化。

1. Zhou Y, Lai CSW#, Bai Y, Li W, Zhao R, Yang G, Frank MG, Gan WB. REM sleep promotes experience-dependent dendritic spine elimination in the mouse cortex, Nature Communications, 2020, 11(1): 4819.

2.  Li Z, Zhang F#, Zhou Y#, Lin M, Zhang B, Wu X, Qiao Q, Gan WB. Rapid eye movement sleep promotes fear conditioning-induced dendritic spine elimination of layer 2/3 pyramidal neurons in the mouse motor cortex, Sleep Research, 2025, 1-15.

3. Zhou Y, Lai B,   Gan WB. Monocular deprivation induces dendritic   spine elimination in the developing mouse visual cortex,  Scientific Reports, 2017,  7(1): 5.4977.

4.  Ji C, Yang X, Eleish M, Jiang Y, Tetlow A, Song S, Ávila AM, Wu Q, Zhou Y, Gan WB, Lin Y, Sigurdsson EM. Neuronal hypofunction and network dysfunction in a   mouse   model   at   an   early stage of   tauopathy,   Alzheimers   Dement,   2024 Nov;20(11):7954-7970.

5. Guo  H, Ali T, Que J, Zhou Y, Bai Y. Dendritic  spine  dynamics in associative memory: A comprehensive review, The FASEB Journal, 2023, 37:e22896.

6. Deng J, Xie H, Chen Y, Peng Z, Zhao J, Zhou Y, Chen C, Zhang K. Comparative study of the reorganization in bilateral motor and sensory cortices after spinal cord hemisection in mice, Neuroreport, 2021, 32(13):1082-1090.

7. Bai Y, Li M, Zhou Y, Ma L, Qiao Q, Hu W, Li W, Wills ZP, Gan WB. Abnormal dendritic calcium activity and synaptic depotentiation occur early in a mouse model of Alzheimer's disease, Molecular Neurodegeneration, 2017, 12(1): 86.

8. Zhang K, Zhang J, Zhou Y, Chen C, Li W, Ma L, Zhang L, Zhao J, Gan W, Zhang L, Tang P. Remodeling the  dendritic  spines  in  the hindlimb representation  of the sensory   cortex    after    spinal    cord   hemisection    in    mice,   PLoS    One,    2015, 10(7):e0132077.

1.  青年科学基金项目，82301351 ，脆性 X 综合征小鼠模型学习记忆障碍相关的 突触可塑性及其机制研究，2024.01-2026.12 ，主持

2.  面上项目，81771428 ，睡眠在衰老过程中对学习记忆的影响及机制研究， 2018.01-2021.12 ，参与